The Afterbirth expansion for The Binding of Isaac: Rebirth was released, adding new items, enemies, bosses, and gameplay modes.
An expansion pack for Afterbirth named Afterbirth+ was released, including mod support and additional content.
The Repentance expansion, the largest content update for The Binding of Isaac: Rebirth, was released, adding substantial new content, quality of life improvements, and a new final chapter.