The United States dropped atomic bombs on the Japanese cities of Hiroshima and Nagasaki, contributing to the end of World War II and marking the first use of nuclear weapons in warfare.
The United States launched the Manhattan Project to develop the first nuclear weapons, leading to technological advancements that would later influence the game's atomic-themed setting.
A severe worldwide economic depression that took place mostly during the 1930s, influencing economic conditions in the mid-20th century and aspects of American culture depicted in the Fallout series.
Bethesda Softworks published Fallout: New Vegas, an action role-playing video game set in a post-apocalyptic Nevada.