Physicist Enrico Fermi achieved the first controlled nuclear chain reaction, paving the way for nuclear power and weaponry.
The world's first nuclear weapon test was conducted in New Mexico, marking the dawn of the atomic age.
Tensions between the United States and the Soviet Union escalated, leading to an era characterized by nuclear arms race and geopolitical rivalry.
A 13-day confrontation between the United States and the Soviet Union over Soviet ballistic missiles deployed in Cuba brought the world close to nuclear war.
The advancement of missile technology during the Cold War increased the threat of global nuclear warfare.
Agreements between the USA and USSR to limit nuclear arms, marking efforts to control the arms race.
Symbolizing the end of the Cold War, this event marked the decline of Soviet influence in Eastern Europe.
Vault-Tec Corporation starts building underground Vaults intended to protect selected populations from nuclear fallout.
Vault 13 is sealed to protect its inhabitants from the nuclear war and fallout outside.
The protagonist, known as The Chosen One, is sent out from Vault 13 to find a water chip to save their Vault's failing water supply.
The Enclave proclaims itself the rightful continuation of the pre-war U.S government and pursues control over remaining resources and territories.
The Chosen One leads the residents of Arroyo against the Enclave's Remnants, securing the survival of the local community.
