Kazuki Yasaka meets a mysterious girl named Kuroha Neko, who warns him about dangerous witches and the organization hunting them.
After helping Hatsuna Wakabayashi, Kazuki learns that she is a witch who escaped from a secret laboratory's experiments.
Kazuki, Hatsuna, Kuroha, and other witches band together to resist the research organization pursuing them.
The group faces off against the organization's assassins sent to eliminate escaped witches.
Kazuki learns details about the cruel experiments that granted witches their powers but threaten their lives.
The group confronts and fights the organization to end the pursuit and give witches freedom.