Photojournalist Frank West arrives in Fortune City to investigate the zombie outbreak and uncover the hidden truths behind the incident.
The zombie outbreak starts spreading rapidly through the casino resort city, leading to chaos and emergency quarantine protocols.
Frank meets the group C.U.R.E., a support group of survivors fighting against zombies, and decides to assist them in escaping the city.
Frank explores various locations in Fortune City, gathering evidence and uncovering that the outbreak was caused by an illegal bioweapon development.
Frank faces off against hostile survivors who have turned violent and threatening during the chaos in the city.
Frank discovers a group of gangsters using customized baseball bats known as Lil’ Sluggers as their weapons, further complicating the situation.
A sudden surge of zombies from the Fort Waterpark area floods a part of the city, endangering survivors including Frank and his allies.
Frank experiences hallucinations caused by exposure to psychovision, which reveals hidden truths and memories about the outbreak and his past.
Frank confronts the corrupted city police Chief Knight, who is tied to covering up the outbreak's origins and exacerbating the crisis.
Authorities enforce city-wide evacuation and quarantines, but survival depends on individual efforts of Frank and remaining survivors.
After uncovering the truth and surviving threats, Frank West manages to escape the quarantined Fortune City, bringing evidence of the outbreak for future exposure.