The television show Desperate Housewives premiered on ABC, introducing audiences to the mysterious and dramatic lives of the residents of Wisteria Lane.
Desperate Housewives won the Golden Globe award for Best Television Series in the Musical or Comedy category, marking a significant achievement and recognition for the show.
The final episode of Desperate Housewives aired, concluding the show's eight-season run and wrapping up the storylines of the main characters.
Mary Alice Young, the neighbor on Wisteria Lane, dies by suicide, sparking the show's central mystery.
Susan and Mike Delfino start their complicated romantic relationship after Mike moves in across from Susan's house.
Lynette Scavo is diagnosed with cancer, significantly impacting her family and storyline.
Rex Van de Kamp, Bree's husband, dies suddenly from a heart condition, deeply affecting Bree's character development.
Gabrielle Solis has an affair with her teenage gardener, John Rowland, complicating her marriage with Carlos.
It is revealed that Zach Young is Mary Alice and Paul Young's son, central to many mysteries and conflicts.
Paul Young is released from prison, returning to Wisteria Lane and shaking up the community.
Katherine Mayfair moves to Wisteria Lane, bringing new dynamics and secrets to the neighborhood.
The neighborhood discovers Mary Alice's secret diaries that explain her reasons for suicide.
Susan Mayer and Mike Delfino get married, marking a high point in their relationship.
