Sony releases the PlayStation 3 gaming console, which will later support Assassin's Creed: Brotherhood.
Microsoft releases the Xbox 360 gaming console, providing a platform for modern gaming titles including Assassin's Creed: Brotherhood.
Ubisoft releases Assassin's Creed II, the predecessor to Assassin's Creed: Brotherhood, setting the stage for its storyline and mechanics.
Ubisoft showcases Assassin's Creed: Brotherhood at E3, announcing its features and release details to the gaming community.
Ubisoft releases Assassin's Creed: Brotherhood worldwide, continuing the story of Ezio Auditore and expanding the series' gameplay elements.
Sony releases the PlayStation 4, marking a new era in gaming platforms though Assassin's Creed: Brotherhood was initially released for previous generation consoles.
Ezio Auditore returns to Rome to find the city under the control of the Borgia family.
Ezio recruits and trains new Assassins in Rome, revitalizing the Brotherhood to oppose the Borgia rule.
Ezio confronts and weakens Cesare Borgia's control over Rome by defeating his key lieutenants and disrupting his power base.
Ezio faces off against Cesare Borgia in a final confrontation at Castel Sant'Angelo, leading to Cesare's defeat and retreat.
With Cesare defeated and the Borgia influence broken, Rome is liberated and the Assassin Brotherhood regains control.
