The first episode of Marvel's Agents of S.H.I.E.L.D. airs on ABC, introducing audiences to a new TV series set in the Marvel Cinematic Universe.
The second season of Marvel's Agents of S.H.I.E.L.D. premieres, continuing the storyline and expanding the show's universe.
Season 3 of Marvel's Agents of S.H.I.E.L.D. debuts on ABC, bringing new characters and story arcs to the series.
The fourth season begins, including the 'Ghost Rider' arc and further exploration of cosmic elements.
The fifth season launches with the storyline focusing on space travel and future timelines.
The sixth season of the series starts, focusing on new threats and deeper character development.
The final season of Marvel's Agents of S.H.I.E.L.D. begins, concluding the story of the agents.
The last episode of Marvel's Agents of S.H.I.E.L.D. airs, wrapping up the series after seven seasons on air.
The formation of the Strategic Homeland Intervention, Enforcement, and Logistics Division (S.H.I.E.L.D.) to handle superhuman and global threats.
S.H.I.E.L.D. introduces an advanced helicarrier program named Project Insight designed for preemptive strike capabilities.
After Hydra infiltration revealed, S.H.I.E.L.D. collapses; Phil Coulson leads rebuilding from underground.
Skye is recruited by Phil Coulson to join S.H.I.E.L.D., beginning her journey into espionage and superhuman exposure.
The discovery of the Inhuman gene changes the nature of threats S.H.I.E.L.D. faces.
The Terrigen Mist is released, triggering the transformation of many individuals into Inhumans.
A virtual reality simulation (The Framework) is created as a prison to control Inhumans.
Mike Peterson is transformed into Deathlok, a cyborg agent under S.H.I.E.L.D.'s control.
Life Model Decoys (LMDs) pose an internal threat to S.H.I.E.L.D., questioning trust within the organization.
Time travel mission to 1930s to prevent Hydra domination, impacting S.H.I.E.L.D.'s history.
Robbie Reyes, aka Ghost Rider, becomes an ally and member of the S.H.I.E.L.D. team.
The Chronicoms arrive on Earth, signaling a new extraterrestrial threat to humanity.
The restoration and operation of the S.H.I.E.L.D. aircraft carrier Enterprise as the mobile base.
Climactic confrontation with the Chronicoms to save Earth and S.H.I.E.L.D.'s future.