A series of brutal murders in the Whitechapel district of London attributed to an unidentified serial killer later known as Jack the Ripper.
The final widely recognized victim of Jack the Ripper, Mary Jane Kelly, is found murdered, marking the end of the canonical series of murders.
The original Sherlock Holmes detective stories by Sir Arthur Conan Doyle are published, popularizing the character who later appears in video games.
The adventure video game combining Sherlock Holmes solving the Jack the Ripper case is released to the public.
The grisly murder of Mary Kelly is discovered in Whitechapel, setting the dark tone for the case.
Detective Sherlock Holmes is called upon to investigate the series of brutal murders attributed to Jack the Ripper.
Holmes interviews Inspector Abberline to gather preliminary evidence and gain insight into the official investigation.
Holmes uncovers critical clues at the latest murder scene that suggest the killer has a medical background.
Holmes confronts a prime suspect believed to be Jack the Ripper, leading to a tense exchange and pursuit through the foggy streets.
Holmes reveals the identity of Jack the Ripper, exposing the motive behind the killings and bringing the case to a close.