Hiromu Arakawa, the creator of the Fullmetal Alchemist manga series, is born.
The Fullmetal Alchemist manga starts serialization in Square Enix's Monthly Shōnen Gangan magazine.
The first anime adaptation of Fullmetal Alchemist debuts, soon becoming a popular series.
Fullmetal Alchemist: Brotherhood, a more faithful anime adaptation, premieres.
The Fullmetal Alchemist manga concludes with its 108th chapter, ending the story.
The live-action adaptation of Fullmetal Alchemist is released in Japan, expanding the franchise into live-action media.
The mother of Edward and Alphonse Elric dies of an illness, which deeply affects the brothers.
Edward and Alphonse Elric attempt to bring their mother back to life using alchemy, violating alchemical laws. The attempt fails disastrously, resulting in Edward losing his left leg and Alphonse losing his entire body. Edward sacrifices his right arm to affix Alphonse's soul to a suit of armor.
Edward Elric obtains the title of State Alchemist by passing rigorous exams, gaining the title 'Fullmetal Alchemist'.
Edward and Alphonse first meet Colonel Roy Mustang, who becomes an important ally and mentor.
The Elric brothers pursue information regarding the Philosopher's Stone to restore their bodies.
The brothers uncover the existence of the Homunculi and their plans associated with the Philosopher's Stone and the government.
Roy Mustang and other characters deal with the consequences of the Ishvalan Civil War and its impact on society.
The Elrics and their allies discover the truth about the leader of the Homunculi and the mastermind behind the Philosopher's Stone experiments: the being known as Father.
Final confrontation with Father and his plans to use Amestris for his godlike ambitions.
After defeating Father, the Elric brothers have their bodies restored, Edward losing his alchemist abilities as a trade-off.
