The medical drama Grey's Anatomy premieres on ABC, introducing viewers to the lives of surgical interns and residents at Seattle Grace Hospital.
The main cast, including Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, and Sandra Oh as Cristina Yang, is finalized before the show's debut.
Second season of Grey's Anatomy begins airing, further developing the characters and increasing the show's popularity.
The show wins the Golden Globe Award for Best Television Series – Drama, recognizing its critical acclaim and popularity.
Season 6 begins featuring a major storyline involving a shooting at Seattle Grace Hospital, marking a dramatic and pivotal event in the series.
Creator Shonda Rhimes signs a new contract with ABC Studios to continue producing Grey's Anatomy and other projects.
ABC announces the renewal of Grey's Anatomy for a record-breaking 15th season, making it one of the longest-running medical dramas on television.
Season 17 filming commences with new health and safety protocols due to the COVID-19 pandemic, affecting production schedules and processes.
The show is renewed for its 18th season, continuing its long-standing run on ABC.
Meredith Grey begins her internship at Seattle Grace Hospital, marking the start of her surgical career.
Derek Shepherd moves to Seattle and joins Seattle Grace Hospital as a neurosurgeon, starting his relationship with Meredith Grey.
The first day of Meredith and her fellow interns at Seattle Grace Hospital, introducing key characters and setting up the main story arcs.
George O'Malley dies from injuries sustained after being hit by a bus, profoundly affecting the hospital staff and storylines.
After a merger and in memory of Lexie Grey and Mark Sloan, the hospital is renamed Grey Sloan Memorial Hospital.
Several main characters survive a plane crash with severe injuries, leading to major personal and professional consequences.
Alex Karev departs from Grey Sloan Memorial Hospital to reunite with Izzie Stevens and their children.
Meredith successfully completes her first solo surgery, marking a milestone in her development as a surgeon.
Izzie Stevens returns to the hospital following a battle with cancer, facing challenges in her professional and personal life.
Meredith Grey is appointed Chief of General Surgery at Grey Sloan Memorial Hospital, reflecting her growth and leadership.
