The TV show Supernatural premiered on The WB network, introducing audiences to the story of brothers Sam and Dean Winchester.
The WB and UPN networks merged to form The CW, where Supernatural continued its broadcast from the second season onward.
Season 5 concluded, originally intended as the series finale before the show was renewed for additional seasons.
The CW announced the renewal of Supernatural for a sixth season, continuing the adventures of the Winchester brothers.
The TV series Supernatural ended after its fifteenth season, concluding 15 years of storytelling.
Sam Winchester is born to John and Mary Winchester.
Dean Winchester is born, the elder son of John and Mary Winchester.
Mary Winchester is killed by the demon Azazel, sparking John Winchester's quest for vengeance.
After Mary's death, John Winchester dedicates himself to hunting supernatural creatures.
Sam Winchester begins his studies at Stanford, initially distancing himself from hunting life.
Sam Winchester's girlfriend Jessica is killed by Azazel, which draws Sam back into the hunting world.
Dean Winchester comes to retrieve Sam to help find their father who has gone missing during a hunt.
The demon Azazel's plan triggers the release of the Four Horsemen and other apocalyptic events.
Dean Winchester makes a deal with a demon, trading his soul for his brother's life.
The angel Castiel rescues Dean from Hell and introduces the Winchesters to heaven and angels.
Crowley, King of Hell, is killed during the effort to stop Lucifer and the apocalypse.
Sam and Dean stop the archangels during the apocalypse, preventing the end of the world.
John dies protecting his sons from a Hellhound.
Sam and Dean discover their family's Men of Letters bunker, gaining access to knowledge and tools.
Sam and Dean face their ultimate challenges and the series concludes with the brothers' fates.
