Production of the science fiction horror film 'Splice' directed by Vincenzo Natali begins.
The film 'Splice' has its world premiere at the Toronto International Film Festival, introducing audiences to its story about genetic engineering and bioethics.
'Splice' is released in theaters across North America, reaching a wider audience with its mix of science fiction and horror.
Genetic engineers Elsa and Clive successfully splice human DNA with animal DNA to create a hybrid creature named Dren.
Dren begins to grow at an accelerated rate, exhibiting unexpected intelligence and behavior uncharacteristic of previously created hybrids.
Dren shows signs of self-awareness and advanced cognitive abilities, behaving in increasingly complex and unpredictable ways.
Due to ethical concerns and corporate interests, Elsa and Clive decide to hide Dren's existence from their employer and the public.
Dren undergoes a drastic physical change, developing humanoid female characteristics, which causes tension between the creators and their creation.
Elsa develops a maternal and ambiguous emotional relationship with Dren, leading to ethical and personal conflicts.
Due to emotional and territorial stress, Dren attacks and injures Clive, raising the threat level of the creature.
Dren kills a nurse who attempts to care for her during an illness, showcasing dangerous and violent behavior.
Recognizing the danger Dren poses, Elsa decides to euthanize her to prevent further harm.
Dren escapes confinement, leading to a destructive confrontation inside the lab facilities.
Elsa confronts Dren in a final encounter that results in Dren's death, concluding the tragic story.
