Richard Matheson's novel 'I Am Legend', on which the movie is loosely based, was published. It became a seminal work in post-apocalyptic fiction.
The first film adaptation of Matheson's novel, titled 'The Last Man on Earth', starring Vincent Price, was released.
The modern film adaptation of 'I Am Legend' starring Will Smith was released worldwide, bringing renewed attention to the story.
A genetically engineered virus meant to cure cancer mutates and starts infecting the human population, leading to a global pandemic.
Governments attempt to quarantine infected zones, but the virus spreads uncontrollably causing societal collapse and mass casualties worldwide.
Virologist Robert Neville remains in New York City, believed to be the last uninfected human.
Neville establishes a routine of collecting supplies, hunting infected, researching a cure, and communicating via radio in the ruins of New York City.
Neville studies infected 'Darkseekers' revealing their nocturnal behavior and sensitivity to UV light.
Neville discovers two survivors, Anna and a young boy named Ethan, leading to cooperation and hope for human resurgence.
Darkseekers assault Neville's fortified home as he tries to save Anna and Ethan, leading to significant losses.
Neville successfully develops a cure from his research and sacrifices himself during a climax to save Anna and Ethan, who escape to a survivor colony.
