Deadpool, created by writer Fabian Nicieza and artist Rob Liefeld, made his first appearance in The New Mutants #98.
Deadpool received his own ongoing solo comic book series, which helped establish his popularity and unique antihero persona.
Writer Dan Way began his acclaimed run on Deadpool, introducing darker tones and deeper character development.
20th Century Fox officially announced the development of a Deadpool movie, starring Ryan Reynolds.
The Deadpool movie, starring Ryan Reynolds and directed by Tim Miller, was released to great box office success and critical acclaim.
Deadpool 2, the sequel to the highly successful first film, was released, continuing the story with more character depth and humor.
After Disney's acquisition of Fox, Deadpool was integrated into the main Marvel Comics Universe under Marvel Studios.
It was announced that Deadpool will be introduced into the Marvel Cinematic Universe with a third solo film produced by Marvel Studios.
Wade Wilson is transformed by the Weapon X program, gaining a regenerative healing factor but suffering severe scarring and mental instability.
Adopting the alias 'Deadpool,' Wade embraces his mercenary lifestyle with a reputation for unpredictability and dark humor.
Deadpool engages in several confrontations with Captain America, showcasing both his combat skills and unpredictable nature.
Deadpool becomes a member of X-Force, a black-ops mutant team, further deepening his involvement in mutant affairs.
Develops a romantic relationship with Vanessa Carlysle, which becomes a significant emotional anchor for Deadpool.
Despite ongoing challenges, Deadpool makes efforts toward managing his mental state and coping with his fractured psyche.
Deadpool confronts and defeats remnants of the Weapon X program that seek to recapture or eliminate him.
Deadpool begins working alongside superheroes like Spider-Man, Avengers, and X-Men in various missions.
Deadpool takes on cosmic threats including Thanos and executes a controversial event where he kills multiple Marvel Universe characters.
Deadpool marries Shiklah, a succubus queen, leading to bizarre adventures blending supernatural and mercenary elements.
Multiple instances of Deadpool dying and returning, demonstrating his healing abilities and narrative resilience.
Deadpool frequently breaks the fourth wall, acknowledging the audience and manipulating his narrative reality.